Anticholinergic risk profiles, clinical and sociodemographic characteristics in a public nursing home in southern Spain: a descriptive study

Authors

  • Elena Prado-Mel Hospital Universitario Vírgen del Rocío. Servicio Andaluz de Salud https://orcid.org/0000-0003-3654-0247
  • Español Hospital Universitario Vírgen del Rocío. Servicio Andaluz de Salud
  • Español Español Hospital Universitario Vírgen del Rocío. Servicio Andaluz de Salud https://orcid.org/0000-0002-8658-120X
  • Español Departamento de medicina preventiva y salud pública. Universidad de Sevilla, Sevilla
  • Español Departamento de medicina preventiva y salud pública. Universidad de Sevilla, Sevilla https://orcid.org/0000-0002-3630-7122

DOI:

https://doi.org/10.60103/phc.v26.e839

Keywords:

Anticholinergic risk; Nursing home; Polypharmacy

Abstract

Objective: to analyze the demographic, clinical and functional characteristics of the elderly in a public nursing home. Characterize the population based on anticholinergic risk according to the Drug Burden Index (DBI) scale. 

Methods: It was carried out a descriptive and observational study in a nursing home of the Andalusian public network from September to December 2020. Demographic, clinical, functional and pharmacotherapeutic outcomes were recorded. Drug treatment was analysed using the DBI scale to determine the anticholinergic load. An association analysis was performed among the different variables studied based on the anticholinergic load.

Results: 148 residents were included. 19.8% of the population was illiterate. 43.9% had smoking and 22.3% consumed alcohol daily. 50.3% had excessive polypharmacy (≥10 medications) and 73.6%. of the patients presented anticholinergic and/or sedative risk according to DBI (defined by presenting a DBI score>0). Delirium, anxiety, and recurrent urinary tract infections were more prevalent in the group of residents with anticholinergic load (p<0.05).

Conclusion: the population of the nursing home has a high rate of illiteracy, and a high prevalence of tobacco and alcohol consumption. The rate of polypharmacy, as well as the percentage of patients with anticholinergic risk associated with pharmacotherapy is high. Anxiety, delirium, and recurrent urinary tract infections were more prevalent in the population with anticholinergic burden. Multicenter studies with a larger number of residents would be necessary to confirm these findings.

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Author Biographies

Elena Prado-Mel, Hospital Universitario Vírgen del Rocío. Servicio Andaluz de Salud

Servicio de Farmacia

Hospital Puerta del Mar (Cádiz)

Español, Hospital Universitario Vírgen del Rocío. Servicio Andaluz de Salud

Farmacéutico Especialista en Farmacia Hospitalaria 

Español Español, Hospital Universitario Vírgen del Rocío. Servicio Andaluz de Salud

Farmacéutica Especialista en Farmacia Hospitalaria

 

Español, Departamento de medicina preventiva y salud pública. Universidad de Sevilla, Sevilla

Assistant professor (Preventive Medicine and Public Health)

Español, Departamento de medicina preventiva y salud pública. Universidad de Sevilla, Sevilla

Profesora Doctora en departamento de Medicina Preventiva de la Facultad de Medicina de la Universidad de Sevilla

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Published

2024-03-16

How to Cite

Prado-Mel, E., Español, Español, E., Español, E., & Español, E. (2024). Anticholinergic risk profiles, clinical and sociodemographic characteristics in a public nursing home in southern Spain: a descriptive study. Pharmaceutical Care España, 26. https://doi.org/10.60103/phc.v26.e839

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