Evaluation of the effectiveness of Personalized Dosing System in the incidence of DRP/NMR and health problems in a community pharmacy. Retrospective cohort study
DOI:
https://doi.org/10.60103/phc.v27.e874Keywords:
Pharmaceutical care; Therapeutic adherence; Community pharmacy; PolymedicatedAbstract
Introduction: Non-adherence to pharmacological treatments in chronic patients is a public health problem, being especially evident in patients with hypertension, diabetes or dyslipidemia.
Method: Retrospective, observational, longitudinal study. 32 patients were divided into two cohorts, with and without SPD, treated with hypoglycemic, antihypertensive or lipid-lowering drugs. An analysis of the DRP/NMR, health problems and interventions were performed. For each patient, cholesterol, glycemia and blood pressure analyses were performed. The correlation between the incidence rate of a DRP/NMR and the rest of the variables was calculated, with calculation of OR (95% CI) and p-value.
Results: 61.1% of patients without SPD are non-adherent and do not pick up or pick up excessively almost 30% of the medication. Non-adherent patients are three times more likely to suffer from hypertension and more than six times more likely to present dyslipidemia (OR: 3.00 and 6.67). The mean values of blood pressure, blood glucose and cholesterol are higher in these patients. The most frequent DRPs in this group of patients are those interaction, probability of adverse effects and untreated health problems. The number of DRPs per treatment is higher in patients without SPD (0.47 vs. 0.42). More than 50% of the interventions propose changes in treatment.
Conclusions: The results support the use of SPD in patients taking multiple medications and with the pathologies studied to reduce the risk of DRP/NMR and improve their biochemical parameters.
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